relation: https://eprints.untirta.ac.id/58553/
title: INOVASI TEKNIK EKSTRAKSI ANTOSIANIN DARI KULIT BUAH NAGA (Hylocereus polyrhizus) MENGGUNAKAN METODE ULTRASONIKASI DAN PROSES PURIFIKASI BERTINGKAT
creator: Salsabilah, Dhiva
creator: Medina Paramitha, Keisha
subject: QD Chemistry
description: The manipulation of materials at the nanoscale through nanotechnology offers significant potential for developing more effective delivery systems for bioactive compounds. This study aimed to obtain the optimal yield of anthocyanin fractions from red dragon fruit peel (Hylocereus polyrhizus), design the synthesis of purified anthocyanins, and produce an anthocyanin nanoemulsion. Extraction was carried out using the ultrasound-assisted extraction (UAE) method with sonication time variations of 3 × 10 minutes, 3 × 15 minutes, and 3 × 20 minutes. The results showed that the 3 × 15-minute sonication produced the highest yield at 19.69%, indicating optimal efficiency in extracting active compounds. The process was followed by multistep purification to obtain purified anthocyanins, which were then formulated into a nanoemulsion. Microscopic characterization revealed an average droplet size of 65.249 nm, which exceeds the ideal nanoemulsion size range (20–200 nm), indicating that the system formed is still classified as a microemulsion. Therefore, further optimization of formulation parameters and homogenization techniques—such as high-pressure processing—is necessary to achieve a nanoemulsion system that meets the required standards for size and stability.
date: 2026-02-18
type: Thesis
type: NonPeerReviewed
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identifier: https://eprints.untirta.ac.id/58553/12/Keisha%20Medina%20Paramitha_3335210092_Fulltext.pdf
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identifier: https://eprints.untirta.ac.id/58553/11/Keisha%20Medina%20Paramitha_3335210092_01.pdf
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identifier: https://eprints.untirta.ac.id/58553/3/Keisha%20Medina%20Paramitha_3335210092_02.pdf
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identifier: https://eprints.untirta.ac.id/58553/4/Keisha%20Medina%20Paramitha_3335210092_03.pdf
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identifier: https://eprints.untirta.ac.id/58553/5/Keisha%20Medina%20Paramitha_3335210092_04.pdf
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identifier: https://eprints.untirta.ac.id/58553/6/Keisha%20Medina%20Paramitha_3335210092_05.pdf
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identifier: https://eprints.untirta.ac.id/58553/7/Keisha%20Medina%20Paramitha_3335210092_Ref.pdf
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identifier: https://eprints.untirta.ac.id/58553/8/Keisha%20Medina%20Paramitha_3335210092_Lamp.pdf
identifier:   Salsabilah, Dhiva and Medina Paramitha, Keisha  (2026) INOVASI TEKNIK EKSTRAKSI ANTOSIANIN DARI KULIT BUAH NAGA (Hylocereus polyrhizus) MENGGUNAKAN METODE ULTRASONIKASI DAN PROSES PURIFIKASI BERTINGKAT.  S1 thesis, Fakultas Teknik Universitas Sultan Ageng Tirtayasa.