relation: https://eprints.untirta.ac.id/44987/
title: PENGARUH SUBSTITUSI PEREDUKSI NH4OH DENGAN MORINGA OLEIFERA PADA SINTESIS Fe3O4 UNTUK APLIKASI BIOSENSOR GIANT MAGNETORESISTANCE
creator: FIRDAUS, FAZRI
subject: QC Physics
description: This study reports a biosensor system based on Giant Magnetoresistance (GMR) chip as transducer and Fe3O4 nanoparticles as magnetic label to detect biomolecules. A commercial chip AAL024 was used as the GMR sensor and to obtain a digital output voltage, the sensor was combined with an Arduino Microcontroller (AM) and a basic differential amplifier. Fe3O4 nanoparticles were synthesized by coprecipitation method and then modified using green synthesis approach utilizing Moringa oleifera (MO) extract to produce GS-Fe3O4. Fe3O4 exhibits a face-centered cubic (FCC) inverse spinel structure with a crystallite size of 9.639 nm. Soft-ferromagnetic behavior was identified for the nanoparticles with low field coercivity and saturation magnetization of 59.18, 64.67 and 30.63 emu/g for Fe3O4, GS-Fe3O4 (1:7) and GS-Fe3O4 (1:3), respectively. These magnetic properties affect the quality of magnetic labels in biosensor applications. The substitution ratio of base reducing agent to MO extract affects the sensitivity of the sensor. The GMR sensor could obtain a signal within 30 s measurement time with high sensitivity of 4.16, 4.61 and 3.71 mV/(mg/mL) and low limit of detection (LOD) of 1.13, 1.02 and 1.66 mg/mL for Fe3O4, GS-Fe3O4 (1:7) and GS-Fe3O4 (1:3). These results show the high sensitivity of the GMR sensor to detect biomolecules. Therefore, GMR chip-based sensors integrated with green synthesis Fe3O4 nanoparticles have strong potential to be designed as competitive biosensor systems.
date: 2024
type: Thesis
type: NonPeerReviewed
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identifier: https://eprints.untirta.ac.id/44987/1/FAZRI%20FIRDAUS_2280210022_FULLTEXT.pdf
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identifier: https://eprints.untirta.ac.id/44987/9/FAZRI%20FIRDAUS_2280210022_CP.pdf
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identifier: https://eprints.untirta.ac.id/44987/2/FAZRI%20FIRDAUS_2280210022_01.pdf
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identifier: https://eprints.untirta.ac.id/44987/3/FAZRI%20FIRDAUS_2280210022_02.pdf
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identifier: https://eprints.untirta.ac.id/44987/4/FAZRI%20FIRDAUS_2280210022_03.pdf
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identifier: https://eprints.untirta.ac.id/44987/5/FAZRI%20FIRDAUS_2280210022_04.pdf
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identifier: https://eprints.untirta.ac.id/44987/6/FAZRI%20FIRDAUS_2280210022_05.pdf
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identifier: https://eprints.untirta.ac.id/44987/7/FAZRI%20FIRDAUS_2280210022_REF.pdf
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identifier: https://eprints.untirta.ac.id/44987/8/FAZRI%20FIRDAUS_2280210022_LAMP.pdf
identifier:   FIRDAUS, FAZRI  (2024) PENGARUH SUBSTITUSI PEREDUKSI NH4OH DENGAN MORINGA OLEIFERA PADA SINTESIS Fe3O4 UNTUK APLIKASI BIOSENSOR GIANT MAGNETORESISTANCE.  S1 thesis, UNIVERSITAS SULTAN AGENG TIRTAYASA.