Amalina, Alya Nur (2025) Hubungan Hasil Pemeriksaan Antibodi Anti-Dengue Imunoglobulin M Dan G Dengan Derajat Trombositopenia Pada Pasien Anak Dengan Demam Berdarah Dengue. S1 thesis, UNIVERSITAS SULTAN AGENG TIRTAYASA.
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Abstract
Background Dengue Haemorrhagic Fever (DHF) causes high morbidity and mortality necessitating rapid and accurate diagnostics,, including platelet count and IgM IgG anti-dengue antibody examination. Previous studies have linked IgM IgG results with thrombocytopenia but without classification by severity, particularly in children who often exhibit more severe symptoms. This study aimed to analyze the association of IgM IgG anti-dengue antibody test results with the degree of thrombocytopenia in pediatric patients with DHF. Methods The study used an observational analytic cross-sectional study, was conducted using medical records and laboratory results of pediatric patients examining platelet counts and anti-dengue IgM IgG antibodies at Banten Regional Hospital (January 2023 - December 2024) with a sample of 178 patients by simple random sampling. Statistical analysis using chi-square test. Results No relationship between the results of IgM IgG anti-dengue antibody examination and the degree of thrombocytopenia in paediatric patients with DHF (p = 0.095). Linear by linear association test showed a significant linear relationship trend (p = 0.030). Conclusion The results of IgM IgG anti-dengue antibody examination are not associated with the degree of thrombocytopenia in paediatric patients with DHF. However, the more severe the degree of thrombocytopenia, the more likely reactive results IgM IgG anti-dengue antibody test.
| Item Type: | Thesis (S1) | |||||||||
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| Additional Information: | Latar Belakang Demam Berdarah Dengue (DBD) menyebabkan morbiditas dan mortalitas tinggi sehingga diperlukan sarana diagnostik cepat dan akurat, diantaranya pemeriksaan jumlah trombosit dan antibodi anti-dengue IgM IgG. Hasil pemeriksaan antibodi anti-dengue IgM IgG dengan trombositopenia telah diteliti tetapi trombositopenia tidak dikategorikan dalam derajat trombositopenia, terutama pada anak yang seringkali menunjukkan gejala lebih berat. Tujuan penelitian ini menganalisis hubungan hasil pemeriksaan antibodi anti-dengue IgM IgG dengan derajat trombositopenia pada pasien anak dengan DBD. Metode Penelitian ini menggunakan studi cross-sectional analitik observasional dengan menggunakan data rekam medis dan hasil laboratorium pasien anak yang melakukan pemeriksaan jumlah trombosit dan antibodi IgM IgG anti-dengue di RSUD Banten (Januari 2023 - Desember 2024). Seleksi 178 sampel dilakukan secara simple random sampling. Analisis statistik menggunakan uji chi-square. Hasil Tidak terdapat hubungan antara hasil pemeriksaan antibodi anti-dengue IgM dan IgG dengan derajat trombositopenia pada pasien anak dengan demam berdarah dengue (p = 0.095). Uji linear by linear association menunjukkan adanya tren hubungan linier yang signifikan (p = 0,030). Kesimpulan Hasil pemeriksaan antibodi anti-dengue IgM dan IgG tidak berhubungan dengan derajat trombositopenia pada pasien anak dengan demam berdarah dengue. Ditemukan semakin berat derajat trombositopenia, maka kemungkinan besar hasil pemeriksaan antibodi anti-dengue IgM dan IgG akan reaktif. | |||||||||
| Uncontrolled Keywords: | Anti-Dengue IgM IgG Antibody, Degree of Thrombocytopenia, Paediatric Dengue Fever, Laboratory Parameters of DHF. Antibodi anti-Dengue IgM IgG, Derajat Trombositopenia, Demam Berdarah Dengue Anak, Parameter Laboratorium DBD. | |||||||||
| Subjects: | Q Science > QR Microbiology > QR355 Virology R Medicine > R Medicine (General) R Medicine > RJ Pediatrics R Medicine > RJ Pediatrics > RJ101 Child Health. Child health services |
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| Divisions: | 07-Fakultas Kedokteran 07-Fakultas Kedokteran > 11201-Prodi Kedokteran |
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| Depositing User: | Alya Nur Amalina | |||||||||
| Date Deposited: | 20 Aug 2025 06:01 | |||||||||
| Last Modified: | 20 Aug 2025 06:01 | |||||||||
| URI: | http://eprints.untirta.ac.id/id/eprint/51367 |
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