Muna, Yumna Anbar (2022) Pengaruh Jarak Ujung Jarum Electrospinning ke Collector terhadap Diameter Serat dan Morfologi Nanofiber PVA/Kolagen/AgNO3 untuk Aplikasi Wound Dressing. S1 thesis, UNIVERSITAS SULTAN AGENG TIRTAYASA.
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Abstract
A wound is defined as tissue damage, such as a trauma or surgical incision that interferes with the anatomy and function of an organ. Wound dressings play an important role in accelerating the wound healing process by closing the wound, absorbing fluid exuding from the wound, relieving pain, and forming new tissue. Nanofibers have attracted attention due to their very attractive properties in biomedical applications, especially for wound dressings. Nanofibers have been shown to be a good wound dressing because of their very small fiber diameter and relatively high porosity, thus preventing microbial growth and dehydration, as well as provide good gas permeability. The manufacture of PVA/Collagen/AgNO3 nanofibers uses the electrospinning method by adjusting the distance from the tip of the needle to the collector with variations of 9 cm, 12 cm, and 15 cm at a voltage of 19 kV, which is done by pressing the syringe pump slowly, which forms a taylor cone with jets that come out slowly and continuously to make the fiber go to the collector. In this study, variation of the distance between the tip of the electrospinning needle to the collector aims to produce a small fiber diameter and its effect on the morphology of PVA/Collagen/AgNO3 nanofibers for wound dressing applications. As the distance from the needle tip to the collector increases, the diameter of the fibers produced by PVA/Collagen/AgNO3 nanofibers will decrease, and the resulting morphological structure has fine and thin fibers but still produces beads. The smallest fiber diameter is found at a distance of 15 cm with a diameter of 228.4 nm and the resulting morphology is not overly beaded.
| Item Type: | Thesis (S1) | |||||||||
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| Additional Information: | Luka didefinisikan sebagai kerusakan jaringan seperti cedera atau sayatan bedah yang mengganggu struktur anatomi dan fungsi organ. Wound dressings mempunyai peran penting dalam mempercepat proses penyembuhan luka seperti menutupi luka, menghentikan pendarahan, menyerap cairan yang keluar dari luka, mengurangi rasa sakit, dan pembentukan jaringan baru. Nanofiber telah menarik perhatian karena karakteristiknya sangat menarik untuk aplikasi biomedis terutama untuk wound dressings. Nanofiber terbukti sebagai wound dressings yang baik karena memiliki diameter serat yang sangat kecil dan porositas yang relatif tinggi, sehingga dapat mencegah pertumbuhan mikroorganisme dan dehidrasi, serta memberikan permeabilitas gas yang baik. Pembuatan nanofiber PVA/Kolagen/AgNO3 menggunakan metode electrospinning dengan mengatur jarak ujung jarum ke collector dengan variasi 9 cm, 12 cm, dan 15 cm pada tegangan 19 kV yang dilakukan dengan menekan pompa jarum suntik secara perlahan yang membentuk taylor cone dengan jet yang keluar secara kontinu untuk membuat serat menuju collector. Pada penelitian ini melakukan variasi jarak ujung jarum electrospinning ke collector bertujuan untuk menghasilkan diameter serat yang kecil dan pengaruhnya terhadap morfologi nanofiber PVA/Kolagen/AgNO3 untuk aplikasi wound dressings. Semakin meningkat jarak ujung jarum ke collector maka diameter serat yang dihasilkan nanofiber PVA/Kolagen/AgNO3 akan menurun dan struktur morfologi yang dihasilkan memiliki serat yang halus dan tipis, tetapi masih menghasilkan beads. Diameter serat terkecil diperoleh pada jarak 15 cm dengan diameter 228,4 nm dan morfologi yang dihasilkan tidak terlalu banyak beads. | |||||||||
| Subjects: | T Technology > TS Manufactures | |||||||||
| Divisions: | 03-Fakultas Teknik 03-Fakultas Teknik > 27201-Jurusan Teknik Metalurgi |
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| Depositing User: | Yumna Anbar Muna | |||||||||
| Date Deposited: | 14 Sep 2022 09:45 | |||||||||
| Last Modified: | 14 Sep 2022 09:45 | |||||||||
| URI: | http://eprints.untirta.ac.id/id/eprint/15522 |
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